The drop-setting step in your crystallography workflow will benefit significantly from the right combination of automated liquid handling instruments.
Run more consistent and reproducible crystallization trials
Eliminate plate contamination and evaporation
Generate consistent, homogenous crystal mixes
No need to vortex or shake the crystallization condition block
Free up time and achieve better results faster
apricot S3 Flexible, automated, high performance liquid handling for a range of applications.
mosquito® Xtal3 Nano-liter pipetting for drop-setting and screening without contamination risk
dragonfly® crystal Non-contact dispensing for crystallization gradients and optimization screens
Workflow steps: Crystallization screen transfers
Place a deep-well block on the deck of an apricot S3 liquid handling instrument (125µL capacity, 96-well tips) to transfer a Hampton crystal screen or equivalent
The apricot S3 mixes the deep-well block, homogenizing the contents without the need to vortex or shake the crystallization condition block
The apricot S3 aspirates the homogenized solutions from the deep-well block with a pre- and post-aspiration air gap
The apricot S3 moves 100µl of solution, minimizing contamination, to the sitting-drop plate or equivalent
The sitting-drop plate is transferred to the mosquito Xtal3, which sets up the miniaturized crystallization trial
The dragonfly crystal can then generate customized crystallization screens for downstream optimization
Consistent, reliable and reproducible crystallisation screens transfers
End-to-end trial workflow in your lab?
Book a tailored crystallography consultation with one of our experts if you would like to discuss implementing an end-to-end trial workflow in your laboratory.
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