Resources

Explore insightful resources that include videos, whitepapers, eBooks, application notes and more

Guidance on 21 CFR Compliance for firefly® Software Version 1.8

firefly Software Version 1.8 offers a suite of tools aimed at streamlining and expediting compliance with 21 CFR Part 11. This document provides an overview of the features and tools included in firefly Software Version 1.8 by SPT Labtech, with specific focus on relevant sections of 21 CFR Part 11.

Technical note

Automated Genotyping with Pneumatic-Assisted Assay Storage and Transport

This poster details how Transnetyx has transformed its TaqMan assay storage and retrieval process to support their automated genotyping services that guarantee results turnaround to researchers within 72 hours.

Poster

Fully Automated Genotyping Powered by Pneumatic Assay Storage and Transport

Automation with comPOUND® has increased throughput to 24-hour operations 6 days/week and enabled scalability to accommodate an annual company growth rate of 15-18%.

Application note

Demonstration of automated KAPA Library Quantification Kits on firefly®

In this poster, for the first time, we demonstrate that KAPA Library Quantification Kits protocols can be successfully automated on SPT Labtech’s firefly® liquid handling platform, to increase throughput and efficiency while delivering consistent and reliable results with no detectable well-to-well contamination.

Poster

firefly® technical note: Automated KAPA Library Quantification

This technical note provides supporting information for automating the KAPA Library Quantification Kits on firefly. These protocols are available to download from the firefly community. Here we give an overview of the protocol run times, consumables usage and share data to demonstrate the performance of these protocols.

Technical note

apricot DC1 Product Overview

Unique dual-core pipetting technology combines the functionality of four pipette tools in one versatile and affordable pipetting platform. With 9 flexible deck positions and automatic tip exchange, the compact apricot DC1 is fully equipped to address a wide range of applications and pipetting tasks.

Video

Scaling Single-Cell Omics With Automated Liquid Handling - Opinionated Science Podcast

By unravelling the complexity of biological systems, single-cell sequencing has proven to be a powerful tool in understanding cellular heterogeneity at an unprecedented resolution, providing valuable new insights into cell development and disease progression. However, achieving high-quality sequencing libraries at scale demands a huge amount of precise, low-volume liquid handling steps that can quickly become a drain on time and resources. In this podcast, we delve into the development of innovative technologies that are overcoming these challenges. We explore how Scale Bioscience’s combinatorial indexing library preparation and the firefly® liquid handling automation platform from SPT Labtech are transforming single-cell sequencing and traditional manual library preparation workflows. By prioritizing scalability, usability and versatility, learn how these technologies work in synergy to deliver a cost-effective solution for labs looking to enhance and streamline their operations.

Video

Revolutionizing NGS-driven Laboratory Developed Tests: The impact of automated liquid handling on plate-based bead clean-up

Automated liquid handling technology is transforming the landscape of Laboratory Developed Tests (LDTs), especially those utilizing Next-Generation Sequencing (NGS), by enhancing accuracy, efficiency and scalability.

Poster

Driving Throughput in tRNA Sequencing Library Generation With Automated Liquid Handling - Webinar

In this webinar, Russel Vincent of the Church Lab and Biopolymers Genomics Core Facility (BPF) at Harvard Medical School will describe how he and colleagues streamlined library generation for tRNA sequencing using SPT Labtech’s Firefly all-in-one automated liquid handling platform.

Webinar

Optimizing multi-cellular models for high-throughput screening - Webinar

Join us as we dive into recent research which has combined Design of Experiments methodology with automated liquid handling to develop a cardiotoxicity assay platform. We discuss how this approach could become routine in the future, not only offering more accurate predictability of new drug candidates, but also enabling researchers to leverage resources more efficiently through streamlined workflows and data-driven decision-making.

Webinar

Scaling up plate-based single-cell profiling: introducing automated STORM-seq

Full-length, single-cell RNA-seq (scRNA-seq) allows for more complete transcriptomic profiling compared to 5' or 3' end-counting methods. However, labor-intensive, non-modular workflows with high reagent costs limit scalability. Advancements in laboratory automation, protocol design, and reaction miniaturization have overcome some of these constraints. In collaboration with the Van Andel Institute, we present Single-cell TOtal RNA Miniaturized sequencing (STORM-seq), which pairs Takara Bio’s SMART® technology with SPT Labtech’s mosquito® HV genomics liquid handling platform. This miniaturized, plate-based scRNA-seq approach is scalable, automated, and offers a solution for single-cell transcriptomic profiling (i.e., coding/noncoding transcripts, isoforms, gene fusions, etc.) at reduced cost and increased cell throughput.

Poster

Scaling single-cell RNA sequencing with automated liquid handling

The ability to obtain and map transcripts from single cells has provided significant insight into the fundamentals of how life persists and how disease evolves. While their plate-based workflows have increased accessibility significantly without requiring specialized instruments, automation of these methods can significantly reduce consumable consumption and streamline processing time while reducing user pipetting errors and strain. This poster outlines the approach, benefits, and results of automating the Scale Biosciences Single Cell RNA Sequencing Kit on SPT Labtech’s all-in-one liquid handling platform, firefly®.

Poster

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