The writer Paul Coelho once said: "If you're brave enough to say goodbye, life will reward you with a new hello". It's an inspiring thought, but in reality, it's natural to be resistant to change and bidding farewell to what has served us well...
Environmental sustainability is high on the agenda for governments worldwide, with private companies, public bodies and academic centers all playing a part in reducing the burden on the world around us. Unfortunately, laboratory research is...
The scale of next-generation sequencing is expanding, and the efficiency of the sequence generation process has improved significantly over time. However, library and sample preparation bottlenecks remain troublesome inhibitors of productivity and...
In the dynamic, fast-paced landscape of genomics research, laboratory heads are constantly challenged to do more with less and deliver greater value from their investment. With the cost of next-generation sequencing reducing year on year, there...
In his book, 'Seven Habits of Highly Effective People', Stephen Covey tells the story of a woodcutter attempting to chop down a tree with a blunt saw. Despite the frustration of working with this ineffective tool, the woodcutter carried on, saying...
Advances in next-generation sequencing have powered a genomic revolution. From early beginnings and painstaking processes, methods have advanced significantly, opening endless research avenues. In 2021, it is now possible to sequence a human genome...
Budget season for lab managers is a tricky time when critical spending decisions need to be taken on competing investment priorities. Staffing costs and the benefits of new laboratory equipment are often weighed up and set against each other. Should...
Recently, we introduced our apricot range of user-friendly liquid handling instruments to the SPT Labtech business. The apricot S3 pipettor is one of the core products in the range, offering automated high-performance 96 and 384 channel pipetting...
As cryo-EM adoption has grown so has the demand to prepare specimen using conventional commercial instruments and DIY set ups. However, most samples exhibit non-ideal behavior and the resulting specimen rarely achieve the reproducible and...
Sample preservation in vitrified ice (vitrification) is widely acknowledged as the first step in the cryogenic electron microscopy (Cryo-EM) workflow. However, prior to sample preparation researchers must consider the sample quality and determine...
The period responsible for the current generation of cryogenic electron microscopy (cryo-EM) instrumentation and image processing software is often referred to as the “resolution revolution.” The results of these technological advancements have been...
The preparation of acceptable frozen-hydrated samples on transmission electron microscopy (TEM) grids is well known to be a challenging bottleneck in the cryogenic electron microscopy (cryo-EM) workflow. During sample vitrification it is assumed...