New technological advances and techniques in Cryo-EM and protein crystallography have inspired a structural biology revolution, enabling researchers to tackle even more complex biological problems to benefit scientific research. ‘Integrative’ structural biology brings together multiple approaches to build a more comprehensive picture of dynamic processes at both a cellular and molecular level.
Transmission electron microscopy is a promising and adaptable technique providing researchers with valuable insights on intricate biological structures ranging from individual biomolecules to whole cells.Explore related products
Cryo-EM has ushered in a new era of scientific discovery with the production of increasingly higher-resolution structural information. Advances in hardware and software have now opened up the technique to more widespread adoption in basic research and drug discovery.Learn more
Single particle analysis (SPA) is a well-established cryo-electron microscopy technique, allowing structural biologists to investigate the detailed structures of macromolecules at near-atomic resolution to uncover rich biological insights.Explore related products
Cryo-electron tomography (cryo-ET) uses 3D molecular-level imaging to produce high-resolution structural and spatial information about individual proteins and the cellular environment where they operate.Explore our range of quantifoil products
Micro electron diffraction (MicroED) is a developing technique for determining the structure of proteins from nanocrystals bringing together cryo-EM sample preparation approaches with electron and X-ray crystallography data analytics.Explore our range of quantifoil products
The automation of protein crystallography screening has made a significant contribution to the rapid expansion of crystallography-based structural biology. Obtaining crystals of a high enough resolution for X-ray diffraction studies can be time and cost intensive, requiring an extensive number of screening and optimization experiments to determine ideal conditions for crystal growth.Learn more
Protein crystallography encompasses a range of techniques such as vapor diffusion and batch crystallization methods to deliver protein structure data in dynamic research environments. Agile solutions are needed to allow researchers to adapt approaches between multiple projects.Check out all methods
Optimizing protein crystallization hits to improve diffraction can be onerous. Automating the preparation of complex gradients from stock solutions saves time, improves repeatability, and increases the output of high resolution structures.Explore related products
Our Field Application Scientists will help you to advance your research goals throughout the life of your instrument, optimizing for the applications you need and harnessing its full potential. As specialists in a range of disciplines including structural biology, the team ensures that the protocols for your applications are scientifically robust, giving you the confidence to pursue novel approaches. Working closely with customers, Field Application Scientists eliminate bottlenecks and streamline workflows to enable successful research outcomes.