Modular automated compound storage at -20°C to ambient. Hermetically sealed chamber under dry air or nitrogen. Pneumatic cherry-picking for fast individual vial retrieval. Scalable modular design - expand capacity without replacing the system.
Designed for compound management workflows, mosquito instruments deliver precise nanoliter transfers with minimal sample loss and zero carry-over between compounds.
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Automated sample and data transfer network connecting storage systems, liquid handlers, and analytical instruments. Eliminates manual sample transport between instruments. Tracks every sample through the compound management workflow with full provenance data.
comPOUND for us invaluable, as we demand a quick reliable service. we get walk away time added by having compound either store or pick vials. These are all ready for the end user, so are kept at the perfect storage temperature. we also get 100% accuracy, which cannot get replicated with human use.
MR Glen - Abcam PLC
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We've been using comPOUND for almost 5 years, and the high-density storage and rapid retrieval system are game changers for our lab. The customer service has always been fantastic. They were responsive and helpful throughout the setup process and continue to provide excellent support whenever needed. Highly recommend this product!
Ratnadeep Bhattacharjee - Corteva Agriscience
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This equipment is very effective for compound management. The original purchase of two modules was expanded to 3 then 4 in a seamless manner. A D2 variant of the store was added some time later for a different sample set. The modularity and scalability of the kit was necessary for a small-medium compound management facility like ours.
David Camp - Griffith University
From the first demonstration to the public in 1999, all the way to how it is today. Explore the interactive timeline of comPOUND with us as we dive into its evolution from a disruptive technology to an industry standard sample management solution.
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Compounds in DMSO degrade through moisture absorption, oxidation, and repeated freeze-thaw cycles. comPOUND stores individual vials in a hermetically sealed, temperature-controlled chamber under dry air or nitrogen, minimizing degradation mechanisms and preserving compound integrity for years. Individual vial retrieval means only the needed compound is exposed - the rest of the library stays sealed.
Compounds are expensive and often available only in limited quantities. Every microliter lost to dead volume is material that cannot be screened or progressed. With dead volumes as low as 0.3 µL per well, the lowest available in any compound management liquid handler, mosquito maximizes recovery from valuable compound stocks while supporting nanoliter-scale transfers for dilution series generation and assay-ready plate preparation. A full dose-response dilution curve can be prepared from less than 1 µL of stock compound.
A single compound contaminant at nanoliter scale can generate false positives in sensitive screening assay. mosquito uses disposable micropipettes with individual pistons for every transfer, eliminating carry-over risk between samples. This is not a wash-and-reuse approach, It is a guaranteed-new-tip approach for every compound contact.
Screening teams need assay-ready plates within hours, not days. Manual compound retrieval, reformatting, and dilution create bottlenecks that delay screening campaigns. The comPOUND + connect + mosquito workflow automates the entire path from compound library to screening plate, with comSTACKER 2 enabling walkaway operation for up to 150 racks without manual intervention.
Regulatory and scientific rigor require complete tracking of every compound: what was stored, when, at what concentration, how many freeze-thaw cycles, where it went, and what was done with it. comPOUND's database and connect's transfer tracking provide full sample provenance, from initial receipt through every storage, retrieval, and liquid handling event.
As compound libraries grow from thousands to hundreds of thousands of entries, manual management becomes impossible. comPOUND's modular architecture allows capacity to scale up without replacing the system, simply add modules. mosquito complements this scalability by delivering consistent low-volume dispensing performance across screening workflows of any scale, from small studies to campaigns supporting libraries of 500,000+ compounds.
| Workflow Stage | Task | SPT Labtech Product | Key Capability |
| Compound Storage | Long-term storage of compound library vials at -20°C under dry/inert atmosphere | 
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Hermetically sealed chamber; individual vial storage; dry air or nitrogen; -20°C to ambient; scalable modular design |
| Cherry-Pick Retrieval | Retrieving specific vials from the compound library on demand |
|
Pneumatic cherry-picking; fast individual vial access without disturbing the rest of the library; full tracking |
| Sample Transfer | Moving retrieved compounds from storage to liquid handling instruments | 
|
Automated sample and data transfer network; eliminates manual transport; full provenance tracking at every step |
| Hit Confirmation and Characterization | Compound pick-up, plate reformatting, serial dilutions and assay-ready plate preparation | 
|
DMSO-compatible nanoliter pipetting; ultra-low dead volumes; rapid plate replication |
| Hit Picking | Cherry-picking confirmed hits for follow-up screening, profiling, and optimization |
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Programmable single-channel access to any well in any plate; rapid pick cycle; CSV Worklists; Cherry Picker II integration |
