Resources | SPT Labtech

Drug Discovery

Development of a 3D high-content imaging based explorative toxicology platform for tumor and healthy colorectal patient-derived organoids.

This study describes the development of an explorative toxicity screening platform using colorectal PDOs obtained from both tumor and matched healthy tissues. The latter is organized into distinct stem cell and differentiated cell compartments with differing proliferative and functional roles, where stem cells maintain homeostasis and self-renewal, and differentiated cells perform specialized functions including drug uptake and barrier maintenance.

Poster

Reimagining Adherent Cell Assays: Flexible Automation with firefly and SemaCyte Technologies

In this joint webinar, Semarion and SPT Labtech walk through the development of robust, automated protocols for dispensing and processing SemaCyte-loaded microwells with minimal manual intervention. Using the firefly, all-in-one liquid handler, the team demonstrates how end-to-end assay automation becomes practical and scalable.

Webinar

Enabling VPS4B Drug Discovery Through a Robust and Miniaturized ATPase Screening Platform

The dragonfly discovery was successfully validated with the Transcreener assay in both 384- and 1536-well formats, demonstrating highly reproducible performance across plate densities.

Poster

firefly - innovative, compact all-in-one liquid handling

Accelerate your genomic research by streamlining your NGS workflows with firefly. View the full brochure here.

Brochure

Bitten by mosquito: The Big Impact of Going Small

In this talk, we’ll look at how SPT Labtech’s mosquito liquid handlers are helping labs tackle those pressures head-on, by enabling reliable, low-volume workflows that are both efficient and scalable. We’ll cover how mosquito is being used in a wide range of applications: from miniaturized NGS and single-cell omics to compound screening to nanoscale chemistry.

Webinar

Automating and Multiplexing Cell Painting Assays

Cell Painting is a high-content imaging assay for producing unbiased morphological profiling of cells, commonly used for mechanism-of-action (MoA) inference, off-target identification, and phenotypic screening in early drug discovery

Case study

Dispensing SemaCytes - Workflow Overview

In this case study learn about the workflow for dispensing Semarion's SemaCytes in combination with the firefly liquid handler.

Case study

Antibody Validation Using Design of Experiment (DoE)

Antibody validation is crucial for assay development, and the gold standard is to perform it across a panel containing both positive and negative cell lines. SemaCytes enable all controls to be housed in a single well, reducing variability and resources needed.

Case study

Automated high-throughput endometrial organoid plating in 100% Matrigel® using firefly®

Matrigel, a reconstituted basement membrane preparation derived from the EHS mouse sarcoma, is a popular matrix used for 3D cell culture. We are presenting an efficient and scalable method of seeding 100% Matrigel-embedded endometrial organoids using SPT Labtech firefly® liquid handler.

Poster

nanoscale synthesis with mosquito®

Explore our flyer for mosquito and its use in nanoscale synthesis and how it is advancing chemistry with ultra-low volume reactions.

Brochure

Compound screening and validation with mosquito®

Explore our flyer on compound screening and validation with mosquito® and how to reduce assay costs without compromising performance

Brochure

mosquito® X1: high speed low volume cherry picking

Download our latest flyer for the mosquito® X1 to discover the key benefits and how it achieves high speed low volume cherry picking.

Brochure

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