Resources

Explore insightful resources that include videos, whitepapers, eBooks, application notes and more

Precision designed for cell-based workflows - Ebook

View our full ebook on precision designed for cell-based workflows using dragonfly discovery.

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Guide
Precision designed for cell-based workflows - Poster

View our one page on precision designed for cell-based workflows using dragonfly discovery.

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Poster
dragonfly® discovery Precision Dispensing - Ebook

View our full ebook on precision dispensing for every stage of discovery using one platform with multiple workflows and endless possibilities, dragonfly discovery.

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Guide
dragonfly® discovery: Assay development meets uHTS

Ultra-high-throughput screening (uHTS) demands homogeneous assay formats to leverage the density of 1536/3456 well plates to increase the throughput of large compound (> 1 million) library screens against disease targets. Such assay formats require automated reagent dispensing and rigorous assay development. The key liquid handlers in any uHTS system are non-contact reagent dispensers rather than tip-based multichannel pipetting devices that are common in many lower throughput assay systems. Critical requirements for any uHTS reagent dispenser are accuracy, precision, and speed. Additionally, it is important to integrate the uHTS dispenser into assay development as early as possible. For most bulk dispensers, this integration typically occurs late in the process. The dragonfly discovery from SPT Labtech is a non-contact positive displacement dispenser designed to bridge dispensing needs from assay development through high-throughput screening. It provides ready access to 10 different reagents that can be dispensed in variable volumes as well as at high speeds. We evaluate the performance of this dispenser in high-throughput mode and examine its use in assay development for reagent concentration optimization in 1536-well plates and buffer component optimization by DOE.

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Poster
The application of Design of Experiment and the dragonfly discovery to miniaturise, automate and accelerate assay optimization

Automation to carry out complex DoE experiments has always been a limiting factor, both in terms of speed and cost. The dragonfly discovery from SPT Labtech, is a rapid and reliable low volume liquid handler that employs true positive displacement technology to enable the dispensing of all aqueous solutions and solvents, from 200nL through to 4mL. The dragonfly discovery's plate-map file format made it simple to convert and import JMP DoE files and subsequently execute these experimental designs in all microplate types, including 1,536 well plates.

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Poster
dragonfly discovery to enable and accelerate early stage drug discovery processes

The complexity of experimental design in early stage drug discovery is rapidly increasing with reagent requirements for a growing number of assays becoming progressively more complex and difficult to dispense. In order to address these challenges, we have utilized the dragonfly discovery to enable a broad range of applications within functional genomics, phenotypic and biochemical assay workflows.

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Poster
SLAS EU 2026 - Crown Bioscience Interview

Peter Van Schaik, a scientist at Crown Bioscience, joined us at our booth at SLAS 2026 to discuss their work with organoid screening and the many bottlenecks they, and many other labs face when working with organoids. High-throughput organoid screening is typically quite labor intensive and costly, however, Peter explained how Crown Bioscience have utilized our firefly all-in-one liquid handling platform to overcome those bottlenecks and achieve things they wouldn’t been able to achieve before and stand out from other labs.

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Interview
Development of a 3D high-content imaging based explorative toxicology platform for tumor and healthy colorectal patient-derived organoids. 

This study describes the development of an explorative toxicity screening platform using colorectal PDOs obtained from both tumor and matched healthy tissues. The latter is organized into distinct stem cell and differentiated cell compartments with differing proliferative and functional roles, where stem cells maintain homeostasis and self-renewal, and differentiated cells perform specialized functions including drug uptake and barrier maintenance.

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Poster
Reimagining Adherent Cell Assays: Flexible Automation with firefly and SemaCyte Technologies

In this joint webinar, Semarion and SPT Labtech walk through the development of robust, automated protocols for dispensing and processing SemaCyte-loaded microwells with minimal manual intervention. Using the firefly, all-in-one liquid handler, the team demonstrates how end-to-end assay automation becomes practical and scalable.

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Webinar
Enabling VPS4B Drug Discovery Through a Robust and Miniaturized ATPase Screening Platform

The dragonfly discovery was successfully validated with the Transcreener assay in both 384- and 1536-well formats, demonstrating highly reproducible performance across plate densities.

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Poster
firefly - innovative, compact all-in-one liquid handling

Accelerate your genomic research by streamlining your NGS workflows with firefly. View the full brochure here.

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Brochure
Bitten by mosquito: The Big Impact of Going Small

In this talk, we’ll look at how SPT Labtech’s mosquito liquid handlers are helping labs tackle those pressures head-on, by enabling reliable, low-volume workflows that are both efficient and scalable. We’ll cover how mosquito is being used in a wide range of applications: from miniaturized NGS and single-cell omics to compound screening to nanoscale chemistry.

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Webinar
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