Resources

Explore insightful resources that include videos, whitepapers, eBooks, application notes and more

Automating and Multiplexing Cell Painting Assays

Cell Painting is a high-content imaging assay for producing unbiased morphological profiling of cells, commonly used for mechanism-of-action (MoA) inference, off-target identification, and phenotypic screening in early drug discovery

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Case study
Dispensing SemaCytes - Workflow Overview

In this case study learn about the workflow for dispensing Semarion's SemaCytes in combination with the firefly liquid handler.

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Case study
Antibody Validation Using Design of Experiment (DoE)

Antibody validation is crucial for assay development, and the gold standard is to perform it across a panel containing both positive and negative cell lines. SemaCytes enable all controls to be housed in a single well, reducing variability and resources needed.

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Case study
Maximizing Library Prep Walkaway Time With Smart, Connected Automation

Hear directly from SPT Labtech scientists and product managers as they walk through key improvements designed to simplify experimental setup and maximize walkaway time.

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Webinar
Automating RNA-seq Library Prep: From Rare Cells to High-Throughput Screens

Join Alithea Genomics and SPT Labtech for an expert-led session on overcoming RNA-seq library prep bottlenecks, from sensitive single-cell workflows to large-scale transcriptomic screens.

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Webinar
Application Note - Illumina DNA PCR-Free Prep

The Illumina DNA PCR-Free Prep kit is an optimized, user-friendly workflow for preparing normalized and ready-to-sequence libraries in under three hours. The workflow is compatible with a broad range of sample types and DNA input amounts, delivering consistent insert sizes, highly uniform coverage across repetitive or uneven genome regions, and is highly compatible with automation.

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Application note
Technical Note - Illumina DNA PCR-Free Prep

This technical note provides supporting information for the firefly protocols listed below. These protocols are available to download from the firefly community. Here, we outline protocol run times, parts required and provide details on the steps performed in each protocol.

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Technical note
A Multi-Pronged Approach to Overcoming Challenges in CryoEM Sample Preparation - Application Note

In this case study, we demonstrate how we combined protein engineering and advanced cryoEM sample preparation using chameleon® to iteratively overcome challenges encountered in structural determination of an ABC Transporter ABCC2. The case study highlights the advantage of Biortus as a full-service gene-to-structure company, capable of offering solutions at various stages of the structural enablement process.

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Application note
Automated high-throughput endometrial organoid plating in 100% Matrigel® using firefly®

Matrigel, a reconstituted basement membrane preparation derived from the EHS mouse sarcoma, is a popular matrix used for 3D cell culture. We are presenting an efficient and scalable method of seeding 100% Matrigel-embedded endometrial organoids using SPT Labtech firefly® liquid handler.

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Poster
PacBio’s 1000 Genomes RNA Sequencing  Project – Automated on firefly®

Explore how PacBio’s 1000 Genomes RNA sequencing project was automated on firefly®

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Brochure
Automating 10x Genomics GEM-X 5’ Gene Expression V3 Library Prep with SPT Labtech’s firefly® to enable screening of over 12M activated primary human T cells

Download our latest poster that details the performance of our firefly liquid handling system for automated 10x Genomics GEM-X 5’ Gene Expression v3 library preparation across three T cell polarization methods.

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Poster
firefly software 2.0 demo

We're excited to share the brand new firefly software 2.0 demo to give you smarter, more connected liquid handling - designed to simplify your science.

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Video
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