mosquito® LCP
Automated membrane protein screening, optimization and scale-up
Incredible power at the heart of your liquid handling processes
reduced set-up time and training requirements
walk-up and use technology which even novice users can master quickly
robust day-to-day performance even in heavy use
proven reliability with no blocking or clogging
protein samples go further and screen consumption is vastly reduced
access volumes as low as 10 nL on multi-aspirate
faster screening of crystallization space for less sample
rapid and accurate drop set-up across a wide viscosity range
flexibility to easily switch methods to suit individual projects
easily set all crystallization methods with no configuration changes
accuracy and precision, irrespective of liquid class
true positive displacement pipetting
Automated lipidic cubic phase screening
mosquito LCP allows you to dispense lipidic cubic phase (LCP) volumes as low as 25 nL, while automated calibration of syringe and pipette positioning ensures precise drop-on-drop placement for easy automated imaging. In addition, mosquito LCP includes all the functionality of mosquito crystal for your automated vapor diffusion set-ups. This allows you to set up both LCP and traditional protein crystallization experiments in any commercially available plate, using just one instrument with no configuration changes, additional hardware or software.
Perfect drops for protein crystallization
mosquito’s unique nanolitre liquid handling technology can perform multiple aspirations before a single dispense, which is essential for automating seeding and direct addition of additive screens to the drops. You can even dispense a combination of solutions simultaneously, with additional mixing if required, ensuring perfect drop formation for optimal protein crystallization.
Humidity control at your fingertips with up to a 90% reduction in drop evaporation
We're revolutionizing liquid handling
Our liquid handling portfolio provides you with accurate and repeatable nanolitre to microlitre pipetting, every time, irrespective of liquid viscosity or environmental conditions.
Built for performance
Our liquid handling instruments use innovative technologies within products to provide real world benefits to researchers.
We produce robust, reliable and easy to use products that overcome difficult technical challenges so that you can focus on solving the scientific ones.
Pipetting technology
Each of our disposable micropipettes has its own individual piston, not an air gap or system liquid, offering true positive displacement pipetting with no risk of cross-contamination.
Humidity control at your fingertips with up to a 90% reduction in drop evaporation
Sample evaporation can be a problem when dispensing very low volumes or volatile samples, causing inconsistent drop volumes, especially when environmental conditions and local humidity vary. mosquito’s active humidity chamber reduces experimental inconsistencies by allowing users to control the relative humidity (RH) of each experiment.
Intuitive by design
Our software is as focused on usability as it is on functionality. We strive for an intuitive user experience that matches the requirements of each scientific application. Through collaboration with scientists, our software team develop and enhance the instrument UI to provide the optimal user experience and facilitate adoption into novel application areas.
Enhance your protein crystallization research
We also offer additional components to enhance your membrane protein crystallization screening, such as a humidity chamber and an automated mixer for preparing LCP.
Featured applications
mosquito liquid handlers have been integrated with a wide variety of other laboratory instrumentation, including robotic plate handlers, stackers and bulk liquid handlers, to achieve walk-away operation in many application areas.
In-meso (LCP) screen set-up
Bicelle setup
Sitting drop
Hanging drop
Microseeding
Microbatch screen set-up
Additive screening
Crystal soaking
Technical specifications
LCP plate
17.3 in (31 in) x 18.5 in x 27 in
What our customers say
The mosquito LCP is our workhorse instrument for the accurate and reliable dispensing of sub-microliter droplet from aqueous and LCP solutions. Reproducibility is key to what we do and the mosquito certainly delivers with excellent speed. Service support is critical to ensuring maximum use of the instrument and the team at SPT Labtech is extremely flexible and deliver to our high expectations.
Related products, accessories and consumables
Consumables
Accessories & spares
Our world-class support commitment
For complete peace of mind our support engineers provide various levels of service and support to suit our customer’s needs, in-house capabilities and expertise.
Technical Support
Service Agreements
Applications Support
Training
Interested? Get in touch to start the journey
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