Resources

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Webinar

Enhancing Core Facility Operations: Automated Liquid Handling for High-Throughput, High-Quality NGS Library Generation

In this webinar, researchers from the Biopolymers Genomics Core Facility (BPF) at Harvard Medical School will discuss automating the versatile NEBNext UltraExpress DNA Library Prep Kit using SPT Labtech’s firefly liquid handling platform to generate high-quality libraries for next-generation sequencing from a broad input range of DNA. The accessible, streamlined NEBNext UltraExpress workflow in tandem with user-friendly firefly creates accessible means for generating NGS libraries for Illumina DNA sequencing. The speakers will explain how the ease of use of the firefly allowed the NEBNext UltraExpress kit to be easily written and optimized for automation and to facilitate a more productive sequencing service.

Webinar

High-throughput nanoscale crystallization for small organic molecules and pharmaceuticals

In this webinar, the methodologies employed in the ENaCt technique will be discussed with case studies highlighting the structural diversity of the method’s applicability, along with the mechanisms for easy access to the technique.

Webinar

How to accelerate small molecule lead discovery with automated multichannel pipetting and DEL technology

Establishing an efficient and accurate compound testing workflow is essential to any small molecule screening platform. When utilizing screening methods such as DNA-encoded library (DEL) technology, follow-up hit validation must be performed using traditional biochemical assays. In this webinar, we will review the use of mosquito LV to accelerate early-stage small molecule lead discovery through the lens of Hydroxyacid oxidase 1 (HAO1). In this case study, we will describe our efforts to develop and deploy a robust enzymatic assay towards the development of potent inhibitors identified by DEL technology for disease treatment.

Webinar

Streamline your liquid handling with scalable, integrated automation - Webinar Recording

Bringing together individual processes into an orchestrated workflow allows you to take a step further. It not only maximizes walk-away time but also fortifies your laboratory with flexible and scalable integrated workflows, ensuring seamless, end-to-end automation that aligns with the diverse needs of both budding biotech startups and established enterprise-level pharmaceutical organizations. In this webinar, experts from SPT Labtech and Biosero will share their specialist knowledge, first exploring the business benefits of combining these powerful technologies. We’ll then take a deeper dive into the practical considerations of implementing integration, sharing insights to give you the highest chance of success.

Webinar

Automating Single-Cell Sequencing Workflows to Generate Cell Atlases

In this webinar, Chan Zuckerberg Biohub San Francisco researchers will discuss the automation of high-throughput plate- and droplet-based scRNA-seq workflows using SPT Labtech’s Firefly system to generate transcriptomic maps, or atlases, for different model organisms such as humans (Tabula Sapiens) and zebrafish (Zebrahub).

Webinar

Elucidating cost-effective miniaturized mRNA-seq library construction and implications for the study of circadian rhythms

Dr. Esser’s group at the University of Florida previously showed that cellular circadian clocks direct a daily transcriptional program that supports homeostasis and resilience. To further learn the age-associated changes in circadian functions, they profiled the circadian transcriptome in different tissues including skeletal muscle, the heart, and others.

Webinar

Driving High-Throughput NGS Library Prep with Automated Liquid Handling

For researchers focused on synthetic biology discovery, the ability to quickly assess large numbers of new constructs is critical to ensuring rapid progress. Scientists want to spend the limited time they have on the confirmation and analysis of their constructs while minimizing labor and costs associated with manipulating samples on the bench. To harness the power of high-throughput NGS analysis of synthetic constructs, laboratories must find ways to ease the burden of library preparation.

Webinar

Webinar - Efficiency redefined: Navigating automated sample management for improved lab performance

While automated processes are known to reduce manual error and provide cost savings for high throughput tasks, it is important to justify a new automated process both operationally and financially. Automation in sample management comes in all different shapes, prices, sizes, and technologies that can help maximize efficiency in laboratories of all disciplines. Given the current economic climate, it is even more crucial to get the most return on investment. In this webinar, Cory Tiller, SPT Labtech will explore the different levels of automation for samples management, and will discuss the benefits from automating these processes, and how considering automation earlier can still provide scalability potential for your lab.

Webinar

Initiating, building, and growing compound management at a small biotech

Compound management is an important and vital part of any organization focused on the development of small molecules for therapeutic use. However, this critical infrastructure is often overlooked in the earliest stages of a company’s growth, which can result in significant challenges for scientists and programs as the company matures.

Webinar

The transition to automated library prep for enhanced pathogen surveillance workflows

Environmental monitoring requires scalable sequencing capabilities to enable communities to make important decisions surrounding public health. Data generated from these localized population studies also helps build phylogenetic trees that further our understanding of infectious disease transmission.

Webinar

Maximize ROI through miniaturization: How to get more for your money in NGS library preparation

To meet the data-demand of modern genomics research, many new methods and technologies have centered around driving throughput in the laboratory. The advent of miniaturized automated liquid handling in particular has played a significant role, enabling scientists to process samples at a much higher rate, up to hundreds at a time.

Webinar

Fast & reliable automation of the NEBNext Ultra II FS DNA library prep kit for Illumina with firefly

Library preparation workflows are labor-intensive and difficult to scale while maintaining quality. As such, they are ideal candidate workflows for automation, allowing scientists to focus on analyzing data rather than generating it. The firefly® liquid handling platform provides complete automation of the liquid handling steps in complex workflows such as library preparation. It does so by combining pipetting, dispensing, shaking, and incubation within a compact benchtop system. The instrument's easy-to-use software makes firefly accessible to anyone in the lab. A unique non-contact dispensing technology helps to reduce plastic waste, while low-volume accuracy enables the miniaturization of common workflows to drive down reagent costs. In this webinar, Paul Lomax, Head of Genomics, and Maryia Karpiyevich, Senior Applications Development Scientist, at SPT Labtech will give an overview of this next-generation liquid handler. They will also present a case study detailing work that was undertaken in collaboration with a UK university core facility where firefly was used to generate libraries using the NEBNext® Ultra™ II FS DNA library kit for Illumina®. Comparative data for samples run both manually and via the automated workflow, including QC and sequencing data, will also be showcased.

Webinar

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