Resources

Explore insightful resources that include videos, whitepapers, eBooks, application notes and more

Webinar

Reimagining Adherent Cell Assays: Flexible Automation with firefly and SemaCyte Technologies

In this joint webinar, Semarion and SPT Labtech walk through the development of robust, automated protocols for dispensing and processing SemaCyte-loaded microwells with minimal manual intervention. Using the firefly, all-in-one liquid handler, the team demonstrates how end-to-end assay automation becomes practical and scalable.

Webinar

Lunch & Learn: Walkaway Automation for mRNA Library Prep: Real-World Implementation and Results

In this Lunch and learn webinar, scientists from the Whitehead Institute Genome Technology Core (GTC) showcased an end-to-end, walkaway automation of the Watchmaker mRNA Library Prep Kit on our firefly+ platform. The team walked through the complete automated workflow, demonstrating how firefly+ performs in real laboratory settings, displaying how complex library preparation processes can be streamlined with automation. Gain insight into how reliable, high-quality library generation can be achieved with minimal hands-on intervention, enabling greater consistency, efficiency, and scalability for transcriptomics workflows.

Webinar

Single-Cell Profiling on Autopilot: Escaping the Manual Bottleneck

Join us as our product manager Kamila Koprowska and Business Development Scientist, Melissa Netwal discuss how automated liquid handling is transforming single-cell workflows, helping scientists reduce hands-on time, improve reproducibility, and scale complex assays with ease.

Webinar

Bitten by mosquito: The Big Impact of Going Small

In this talk, we’ll look at how SPT Labtech’s mosquito liquid handlers are helping labs tackle those pressures head-on, by enabling reliable, low-volume workflows that are both efficient and scalable. We’ll cover how mosquito is being used in a wide range of applications: from miniaturized NGS and single-cell omics to compound screening to nanoscale chemistry.

Webinar

Maximizing Library Prep Walkaway Time With Smart, Connected Automation

Hear directly from SPT Labtech scientists and product managers as they walk through key improvements designed to simplify experimental setup and maximize walkaway time.

Webinar

Automating RNA-seq Library Prep: From Rare Cells to High-Throughput Screens

Join Alithea Genomics and SPT Labtech for an expert-led session on overcoming RNA-seq library prep bottlenecks, from sensitive single-cell workflows to large-scale transcriptomic screens.

Webinar

Automating large-scale isoform discovery at Seattle Children’s Genomics and Spatial Biology CoLab

In this webinar Dr. Rebecca Martin, Scientific Lead of the Genomics and Spatial Biology CoLab at Seattle Children’s Research Institute and Dr. Liz Tseng, Product Manager at PacBio, discuss how automation is transforming long-read transcriptomics.

Webinar

Restoring Nature with NGS: The Role of Automation in Conservation Science

In this webinar, Kedrick Mckissock will discuss how cutting-edge genomics helps scientists forge a path towards ecological recovery and species revival.

Webinar

Automating and Scaling Binder Discovery for Next-Generation Therapeutic Biologics

In this webinar, Christian Soule, director of automation and Anna Southworth, senior research associate, at the Broad Institute, will detail the automated selection and RNA recovery stages of the RABIT workflow utilizing the firefly liquid handler.

Webinar

Automating RNA Library Prep for High-Throughput Genomics: AstraZeneca Case Study

In this session, Sara Talbot, Senior Research Scientist at AstraZeneca, shares her experience using the NEBNext UltraExpress RNA Library Prep Kit in combination with our firefly platform to prepare 96 RNA-seq libraries in a single day. This powerful integration of reagents and automation not only streamlined the library preparation process but also significantly reduced time at the bench and improved reproducibility across samples.

Webinar

Optimizing NGS library prep in the Core lab

As sequencing costs continue to decrease, sample and library preparation have emerged as the critical bottleneck in modern genomics workflows. Core facilities face mounting pressure to process thousands of samples with accuracy and precision while maintaining competitive pricing and rapid turnaround times. In this session, you'll hear from Taylor Fennelly, a researcher at the Biopolymers Facility (BPF) at Harvard Medical School, who will share their success story implementing SPT Labtech’s firefly for high-throughput, high-quality library generation. Our very own firefly product manager, Denise Grovewood will demonstrate how this compact, all-in-one automated liquid handling solution is specifically designed to overcome the bottlenecks faced by sequencing cores.

Webinar

Generating Bespoke Datasets for Foundation Models in AI Drug Discovery

The application of AI in drug discovery relies on high-quality, reproducible training datasets. Traditional screening campaigns focus on identifying potent hits, but ML-driven drug discovery requires comprehensive potency evaluation across entire compound libraries. Here, we introduce a partial concentration-response curve (pCRC) approach that estimates potency using just two data points per compound. We onboarded a panel of 65 diverse kinases and screened 7000 compounds against the panel at ATP concentrations near Kₘ to minimize modality bias, achieving a mean robust Z’ of 0.74 across all targets. A direct comparison of 100 fragments tested in both 2-point pCRC and conventional 11-point CRC formats demonstrated excellent correlation, confirming that our pCRC methodology produces high-quality data suitable for ML model training. The integration of our automation platform, including SPT Labtech’s dragonfly® discovery, with automated data pipelines enabled the generation of 221,000 high-quality ML-ready data points per day, accelerating the development of foundation model training for drug discovery.

Webinar

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