mosquito® crystal
The crystallographers' favorite liquid handler
Incredible power at the heart of your liquid handling processes
reduced set-up time and training requirements
walk-up and use technology which even novice users can master quickly
robust day-to-day performance even in heavy use
proven reliability with no blocking or clogging
protein samples go further and screen consumption is vastly reduced
access volumes as low as 10 nL on multi-aspirate


faster screening of crystallization space for less sample
rapid and accurate drop set-up across a wide viscosity range
flexibility to easily switch methods to suit individual projects
able to set-up all traditional (non-LCP) protein crystallization experiments
accuracy and precision, irrespective of liquid class
true positive displacement pipetting
Get the most from your precious protein samples
With mosquito crystal, you can use smaller volumes of precious protein sample with no risk of cross-contamination. This results in cost savings and allows more extensive screening. You can automate all the popular protein crystallization screening techniques (hanging drop, sitting drop and
Perfect drop formation for optimal protein crystallization
mosquito’s unique nanolitre liquid handling technology can perform multiple aspirations before a single dispense, which is essential for automating seeding and direct addition of additive screens to the drops. You can even dispense a combination of solutions simultaneously, with additional mixing if required, ensuring perfect drop formation for optimal protein crystallization.


Bring the benefits of positive displacement pipetting into your lab
We're revolutionizing liquid handling
Our liquid handling portfolio provides you with accurate and repeatable nanolitre to microlitre pipetting, every time, irrespective of liquid viscosity or environmental conditions.
Built for pure performance
Our liquid handling instruments use innovative technologies within products to provide
We produce robust, reliable and easy to use products that overcome difficult technical challenges so that you can focus on solving the scientific ones.
Pipetting technology
Each of our disposable micropipettes has its own individual piston, not an air gap or system liquid, offering true positive displacement pipetting with no risk of cross-contamination.
Humidity control at your fingertips with up to a 90% reduction in drop evaporation
Sample evaporation can be a problem when dispensing very low volumes or volatile samples, causing inconsistent drop volumes, especially when environmental conditions and local humidity vary. mosquito’s active humidity chamber reduces experimental inconsistencies by allowing users to control the relative humidity (RH) of each experiment.
Intuitive by design
Our software is as focused on usability as it is on functionality. We strive for an intuitive user experience that matches the requirements of each scientific application. Through collaboration with scientists, our software team develop and enhance the instrument UI to provide the optimal user experience and facilitate adoption into novel application areas.
Enhance your protein crystallization research
We also offer additional components to enhance your protein crystallization screening, such as a humidity chamber and spool cover.
Featured applications
mosquito liquid handlers have been integrated with a wide variety of other laboratory instrumentation, including robotic plate handlers, stackers and bulk liquid handlers to achieve walk-away operation in many application areas.
Sitting drop




Hanging drop




Microseeding




Microbatch screen set-up




Screen optimization




Bicelle set-up




Additive screening




Crystal soaking




Encapsulated Nanodroplet Crystallization (ENaCt)




Technical specifications
15.5 in (31 in) x 18.5 in x 27 in
What our customers say
The mosquito is a wonderful addition to our University. It can do in less than 5 minutes what takes me to do in more than 8 hours. The nanolitre liquid handling capabilities produces drop size and placement speed that are not humanly possible.
Our world-class support commitment
For complete peace of mind our support engineers provide various levels of service and support to suit our customer’s needs, in-house capabilities and expertise.
Technical support




Service Agreements




Applications Support




Training






Interested? Get in touch to start the journey
Ask an expert