Resources (15)

Screening

Heap, R., et al. (2019). Profiling embryonic stem cell differentiation by MALDI-MS: development of a reproducible and robust sample preparation workflow. bioRxiv

Screening

Reinke, A., et al. (2019). Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate. Journal of Biological Chemistry

Screening

Winter, M., et al. (2019). Automated MALDI Target Preparation Concept: Providing Ultra-High-Throughput Mass Spectrometry–Based Screening for Drug Discovery. SLAS TECHNOLOGY: Translating Life Sciences Innovation

Screening

Schaaf, T., et al. (2018). Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening. Biosensors

Screening

Winter, M., et al. (2018). Establishing MALDI-TOF as versatile drug discovery readout to dissect the PTP1B enzymatic reaction. SLAS DISCOVERY: Advancing Life Sciences R&D

Screening

Lo, C., et al. (2018). A novel small molecule screening platform for disrupting toxic tau oligomers in cells. bioRxiv

Screening

Jamieson, S., et al. (2018). Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1. Sci. Signal.

Screening

De Cesare, V., et al. (2018). The MALDI-TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway. Cell chemical biology

Screening

Guhathakurta, P., et al. (2018). High-throughput screen, using time-resolved FRET, yields actin-binding compounds that modulate actin-myosin structure and function. Journal of Biological Chemistry

Screening

Peng, T., et al. (2018). Scope and limitations of carbohydrate hydrolysis for de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimetic. Carbohydrate research

Screening

Lorenz, D., et al. (2018). Development and implementation of an HTS-compatible assay for the discovery of selective small-molecule ligands for pre-microRNAs. SLAS DISCOVERY: Advancing Life Sciences R&D

Screening

Foote, P., et al. (2018). High‐Throughput Screening of HECT E3 Ubiquitin Ligases Using UbFluor. Current protocols in chemical biology

Interested? Get in touch to start the journey

Find help through our cross-domain support package

Find out where you can see our technologies in action

Get up to speed with our news