dragonfly discovery
Webinar: tabula muris, a single cell atlas of the adult mouse
Lipidic Cubic Phase (in-meso)
Apel, A., et al. (2019). Crystal structure of CC chemokine receptor 2A in complex with an orthosteric antagonist provides insights for the design of selective antagonists. Structure
Hanging drop crystallization, Sitting drop crystallization
Ejby, M., et al. (2019). Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β‐mannan possess distinct manno‐oligosaccharide‐binding profiles. Molecular Microbiology
Sitting drop crystallization
Chandra, M., et al. (2019). Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nature communications
Sitting drop crystallization
Lisa, M., et al. (2019). Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor. Nucleic acids research
High throughput transcriptomics
Rodriguez-M., et al. (2019). Unraveling intratumoral heterogeneity through high-sensitivity single-cell mutational analysis and parallel RNA sequencing. Molecular cell
Screening
Heap, R., et al. (2019). Profiling embryonic stem cell differentiation by MALDI-MS: development of a reproducible and robust sample preparation workflow. bioRxiv
Screening
Reinke, A., et al. (2019). Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate. Journal of Biological Chemistry
Screening
Winter, M., et al. (2019). Automated MALDI Target Preparation Concept: Providing Ultra-High-Throughput Mass Spectrometry–Based Screening for Drug Discovery. SLAS TECHNOLOGY: Translating Life Sciences Innovation
Screening
Schaaf, T., et al. (2018). Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening. Biosensors
Screening
Winter, M., et al. (2018). Establishing MALDI-TOF as versatile drug discovery readout to dissect the PTP1B enzymatic reaction. SLAS DISCOVERY: Advancing Life Sciences R&D
Screening
Lo, C., et al. (2018). A novel small molecule screening platform for disrupting toxic tau oligomers in cells. bioRxiv