Webinar recording:
Developing a miniaturized DNA-seq method to reduce costs with a next generation liquid handling platform

This must-see webinar showcases a high-throughput, low-volume library preparation method for whole-genome sequencing (WGS) developed by the Earlham Institute.

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About this webinar recording

Thomas Brabbs, Senior Research Assistant at the Earlham Institute, presents a miniaturized version of the Illumina DNA Prep method that was developed in collaboration with SPT Labtech for the all-in-one firefly® liquid handling platform for genomics.

He discusses how WGS data obtained from human controls and a mock bacterial community with variable GC content prepared using the miniaturized DNA Prep libraries compare to the full-volume protocol as well as to the lab’s current low-input Nextera method. The focus of this comparison will be on genome coverage and GC bias.

Key learnings:

  • Overview of the miniaturized DNA Prep protocol on the SPT Labtech firefly platform.
  • Comparison of miniaturized libraries with full-volume libraries.
  • Utility of low-cost library construction for genomic studies.

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